Regioselective one-pot, three component synthesis of ethyl 6-aryl-3-propylpyridazine-4-carboxylates in water


Jabbar Khalafya, Mehdi Rimaz and Mahnaz Ezzati


A regioselective synthesis of ethyl 6-aryl-3-propylpyridazine-4-carboxylates by one-pot three-component reaction of ethyl butyrylacetate with various arylglyoxals in the presence of hydrazine hydrate at room temperature in water was described.


DOI: j.ccl.2012.6.001

Keywords: Pyridazine ,Arylglyoxal ,Hydrazine ,Regioselective

How to cite this paper:

Khalafya, J., Rimaz, M & Ezzati, M. (2012). Regioselective one-pot, three component synthesis of ethyl 6-aryl-3-propylpyridazine-4-carboxylates in water.Current Chemistry Letters, 1(3), 115-122.


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